Tickling the Retina: Charting the Future of Bionic Sight Restoration
- Date and time: October 10, 2017 from
11:00am –12:00pm
- Location: BiocomplexityInstitute Conference Room
- Speaker: Daniel Rathbun, Ph.D.
Principal Investigator
Experimental Retinal Prosthetics Group. University of Tuebingen
Ashumanlifeexpectancyincreases,blindnessandvisualimpairmentduetodegenerationofthelightresponsivecellsoftheeye–photoreceptors–becomesevermoresignificant.Hundredsoflaboratoriesarepursuingsolutionstothisproblem.Todate,oneofthemostsuccessfulapproacheshasbeentheimplantationofdevices–likeTuebingen’sAlpha-AMSimplant–toelectricallystimulatetheremainingneuronalcellsoftheeye.Respondingtoinputfromanelectroniccameratheseneuronsthencommunicatevisualinformationtothebrain.Thusthenaturalvisionthathasbeenlosttoblindpatientsisreplacedwithbionicvision.
Thethinnetworkofneuronsliningtheinnersurfaceoftheeye,calledtheretina,hasmanyparallelinformationprocessingchannels.Asaresult,theganglioncellswhichpassinformationtothebrainconsistofdozensofdifferfunctionaltypes.Ensuringthatbionicretinalimplantsfullyexploitthisdiversityofinformationchannelshasbeenalong-termgoalofbionicvisionresearch.Topursuethisgoal,wehaveappliedthemethodsoflinearsystemanalysistoelectricalstimulationoftheretina.
Inthispresentation,IwilldescribethestatusoftheAlphaAMSretinalimplant.Then,throughasystematicevaluationoftheelectricalstimulusparameterspace,Iwilldiscusstheresponsivenessoftheretinalnetworktoprostheticstimulation.Next,IwilldescribehowtheExperimentalRetinalProstheticsGroupinTuebingenhasdevelopedalinearsystem-basedmethodformoreefficientlyprobingretinalresponsestoelectricalstimuli.Finally,Idiscussthenearfutureoftheseeffortsandtheirpotentialimpactonblindpatientssufferingfromdegenerativediseasessuchasretinitispigmentosaandmaculardegeneration.
Contact Anne Wailes for more information: awailes@vt.edu